Non-metastatic castration resistant prostate cancer (nmCRPC) is defined as a disease state withlack of topo designs cooler bag radiographic evidence of metastatic disease, a confirmed rising PSA level on continuous ADT and maintaining a castrate level of testosterone following definitive therapy.Prior to the publication of PROSPER, SPARTAN and ARAM
Anaphylactic shock is a life-threatening condition which needs detailed and mediculous clinical assessment and thoughtful treatment.Several causes can join forces in order to degranulate mast cells.Amiodarone which is an iodine-containing highly lipophilic benzofuran can induce allergic reactions and anaphylactic shock in sensitized patients.Epinep
Tsunami attenuation by coastal vegetation was examined under laboratory conditions for mature mangroves <i>Rhizophora</i> sp.The developed novel tree parameterization concept, accounting for both bio-mechanical and structural tree properties, allowed to substitute the complex tree structure by a simplified tree model of identical enforc
For the Early Neolithic lithic industry in Western Europe (5500-4800 BCE), the study of technical behaviors, recognition of technical traditions, and even more so, idiosyncratic manifestations are not widespread.In this study, we propose an original approach to lithic industries based on the identification of "communities of practice" and individua
Abstract Background Noonan and Noonan-like syndromes are multisystem genetic disorders, mainly with autosomal dominant trasmission, caused by mutations in several genes.Missense pathogenetic variants of SOS1 gene are the second most common cause of Noonan syndrome (NS) and account approximately for 13% to 17% of cases.Subjects carrying a pathogenet